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一 | Are 3D mammograms better than standard 2D imaging for catching advanced cancers?A clinical trial is recruiting thousands of volunteers — including a large number of Black women who face disparities in breast cancer death rates — to try to find out.People like Carole Stovall, a psychologist in Washington, D.C., have signed up for the study to help answer the question.“We all need a mammogram anyway, so why not do it with a study that allows the scientists to understand more and move closer to finding better treatments and ways of maybe even preventing it?” Stovall said.The underrepresentation of women and minorities in research is a long-simmering issue affecting health problems including Alzheimer’s disease, stroke and COVID-19. Trials without diversity lead to gaps in understanding of how new treatments work for all people. “Until we get more Black women into clinical trials, we can’t change the science. And we need better science for Black bodies,” said Ricki Fairley, a breast cancer survivor and advocate who is working on the issue.Black women are 40% more likely to die from breast cancer than white women and tend to be diagnosed younger. But it’s not clear whether 3D mammography is better for them, said Dr. Worta McCaskill-Stevens of the National Cancer Institute.“Are there populations for whom this might be important to have early diagnosis?" asked McCaskill-Stevens. "Or is it harmful,” causing too many false alarms or unneeded follow-up tests and treatments?McCaskill-Stevens, who is Black, leads NCI’s efforts to boost access to cancer research in minority and rural communities. She has joined the study herself.The newer 3D technique has been around for a decade, but there’s never been conclusive evidence that it's better than 2D at detecting advanced cancers. The screening technique combines multiple pictures of the breast taken from different angles to create a 3D-like image. Both 3D and 2D mammograms compress the breast and use low doses of radiation.Prior studies suggest that 3D finds more cancers than 2D, but catching more cancers doesn’t necessarily mean more lives saved. Some cancers missed by standard screening may not progress or need treatment. Previous studies did not randomly assign patients to a screening method, the gold standard for research.The notion “that if it’s new, it’s shiny, then it’s better,” isn’t necessarily true, McCaskill-Stevens said. “Until we have the evidence to support that, then we need well-designed randomized trials.”The trial has enrolled nearly 93,000 women so far with a goal of 128,000. The NCI-funded study is now running in Canada, South Korea, Peru, Argentina, Italy and 32 U.S. states. A site in Thailand will soon begin enrolling patients.“We added more international sites to enhance the trial’s diversity, particularly for Hispanic and Asian women,” said Dr. Etta Pisano, who leads the study. Overall, 42% of participants are Hispanic. As recruiting continues, enrolling Black women and other women of color will “absolutely” continue as a priority, Pisano said.Participants are randomly assigned to either 2D or 3D mammograms and are followed for several years. The number of advanced cancers detected by the two methods will be compared.At the U.S. study sites, 21% of study participants are Black women — that's higher than a typical cancer treatment study, in which 9% of participants are Black, McCaskill-Stevens said.The University of North Carolina has signed up more Black women than any other study site. Nearly a quarter of the nearly 3,000 women enrolled at UNC’s two locations are Black.“Women in North Carolina want to take part in something that’s bigger than them,” said Dr. Cherie Kuzmiak, who leads the UNC arm of the study. “They want this active role in helping determine the future of health care for women.”In Washington, D.C., word of mouth has led to successful recruiting. A chance encounter at her hair salon persuaded Stovall to join the research. While waiting for a hair appointment, she met Georgetown University cancer researcher Lucile Adams-Campbell. The two, both Black, started chatting.“She explained how important it was to get women of color into the program,” said Stovall, who jumped at the chance to catch up on her mammograms after the COVID-19 pandemic delayed screening for her and thousands of others.For Stovall, there was a personal reason to join the research. Her sister recently completed treatment for triple negative breast cancer, an aggressive type that affects Black women at higher rates than white women. Women ages 45 to 74 without a personal history of breast cancer are eligible for the study, which launched in 2017. Many women also are providing blood and cheek swab samples for a database that will be mined for insights.“It’s a dream that people had since the beginning of screening that we wouldn’t fit everybody into the same box,” Pisano said. The study's findings could “reduce disparities if we’re successful, assuming people have access to care.”Stovall, 72, had a brief scare when her mammogram, the traditional 2D type, showed something suspicious. A biopsy ruled out cancer.“I was extremely relieved,” Stovall said. “Everybody I know has heard from me about the need for them to go get a mammogram.”___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.。

二 | 디지털엑스 임직원 초청 행사서 강연 박현주 미래에셋그룹 회장이 26일 서울 포시즌스호텔에서 열린 디지털엑스 임직원 초청 행사에서 강연을 하고 있다. 미래에셋증권 제공"단순히 주식이나 코인을 사고파는 세상은 5년 안에 없어질 겁니다. 앞으로 삼성전자, SK하이닉스 같은 대형주를 잘게 나눠서 토큰화하거나, 전기·금 등 실물자산을 코인과 연계하는 등 자산 간 경계가 허물어지는 시대가 올 겁니다."박현주 미래에셋그룹 회장 겸 글로벌전략가(GSO·사진)는 26일 서울 광화문 포시즌스호텔에서 열린 디지털엑스 임직원 초청 행사에서 이렇게 말했다. 디지털엑스는 국내 4위 가상자산거래소 '코빗'의 운영사로, 올 7월 미래에셋그룹에 최종 인수됐다. 이번 행사는 미래에셋그룹의 품에 안긴 디지털엑스의 새 출발을 기념하고, 그룹의 중장기적 비전을 공유하기 위해 박 회장이 직접 마련했다.이날 박 회장은 '미래에셋 3.0' 체제에서 디지털엑스가 맡게 될 핵심 역할과 향후 사업 방향 등을 공유했다. 그는 "투자란 것은 고정관념에서 벗어난 새로운 사고 전환이 필요하다"며 "디지털엑스를 통해 크립토(암호화폐)뿐 아니라, 스테이블코인, 실물연계자산(RWA), 토큰증권(STO) 등을 아우르는 디지털 금융 인프라를 구축할 것"이라고 했다.특히 박 회장은 전통자산과 디지털자산을 융합하는 RWA를 강조했다. 그는 "비트코인을 '디지털 금'이라고 하지만 만져본 적이 없지 않냐"며 "최근 각국 중앙은행이 금을 매입하고 있는데, 실물 금을 기반으로 '디지털 금 코인'을 20조~30조원 규모로 형성하면 투자자에게 엄청난 기회가 될 것"이라고 했다. 이어 "AI 시대에 전기가 가장 중요해지면서 가격이 상승할 텐데, 이를 기반으로 '전기 코인'을 발행하면 전기료 상승 가치를 담아낼 수 있다"고 덧붙였다. STO에 대해서도 "반드시 가야 하고, 갈 수밖에 없는 시장"이라고 말했다. 그는 "삼성전자 등 대형주를 슬라이싱해서 STO로 내놓으면 어마어마한 시장이 열릴 것"이라고 했다.박 회장은 "현재 1500조원 규모의 미래에셋그룹 고객 자산 중 150조원 이상을 디지털 자산으로 전환할 것"이라고도 강조했다. 이에 따라 지난해 154억원의 손실을 냈던 디지털엑스가 흑자 전환할 것으로 봤다. 디지털엑스의 자본 확충 방안과 관련해선 "내년 1분기 2000억~3000억원 규모의 제3자배정 유상증자를 시행할 것"이라고 했다.박 회장은 이날 행사에서 최근 국내 증시에 대한 관점도 공유했다. 그는 "한국의 자본시장은 이미 세계 5위 규모로 성장했다"며 "투자자는 주가가 1000~2000원 떨어지는 것을 두려워하기보다 장기적인 기업의 펀더멘털을 믿고 봐야 한다"고 했다. 삼성전자가 대규모 주주환원책을 내놓고도 주가가 하락한 것에 관해서는 "배당도 중요하지만, 결국엔 자본을 축적해 미래에 과감하게 투자하는 회사가 잘되는 것"이라고 강조했다.미래에셋그룹이 선제적으로 투자한 스페이스X와 관련해선 "유니크함과 혁신을 모두 갖춘 회사"라며 "새틀라이트(위성) 사업뿐 아니라, AI 데이터센터 임대 등으로 연말에 흑자를 낼 것으로 기대한다"고 했다. 미래에셋증권은 스페이스X 지분 투자 효과로 올 2분기 1조9052억원에 달하는 순이익을 기록했다. 증권사 1위는 물론, 신한·국민·하나·우리·농협 등 5대 시중은행의 이익마저 제쳤다.。
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